HSE, in collaboration with the Environment Agency, has developed guidance for registrants on meeting the toxicological and ecotoxicological information requirements laid out in Annexes 7-10 of UK REACH. Specifically, the guidance outlines ways in which new tests on animals might be avoided or minimised.

Many opportunities to minimise animal testing are available and registrants are reminded that any animal tests must only be undertaken as a last resort and implementing the 3Rs (Reduction, Refinement and Replacement).

Registrants should use this guidance when considering how to meet information requirements in the UK REACH annex(es) relevant to their registration tonnage band.

The guidance primarily applies to the registration of new substances, that is, those that were not registered under EU REACH before the 1 January 2021.

Registrants must submit a testing proposal to the Agency for any Annex 9 and 10 testing by way of a dossier update in line with Article 40 of UK REACH.

View guidance on the minimisation of animal testing under UK REACH.